BJY-PeptaLift-4 is an anti-aging peptide ingredient composed of 17 amino acids. 

By inhibiting SNARE complex formation, it helps prevent the appearance of wrinkles associated with muscle contraction and 

supports improved skin elasticity.

Improves Expression Wrinkles
Inhibits SNARE complex formation, helping prevent and improve the appearance of expression wrinkles caused by muscle contraction.

Inhibits Muscle Contraction Signaling
At 10 ppm, BJY-PeptaLift-4 inhibited acetylcholine release by 34.31%, thereby reducing signaling associated with muscle contraction.

Improves Skin Elasticity
Inhibited elastase activity by up to 35.8%, helping maintain skin elasticity.

Promotes Collagen Production
Increased a Type I procollagen-related marker by up to 66.9%, helping support collagen production.

Improves Eye-Area Wrinkles
In a 4-week human application study using an eye cream containing 100 ppm BJY-PeptaLift-4, eye-area wrinkles improved by 21.52%.

Acetylcholine Secretion Inhibition Assay

Treatment with BJY-PeptaLift-4 at 10 ppm inhibited acetylcholine secretion by 34.31%

< Acetylcholine secretion inhibition assay using a co-culture model of human dermal fibroblasts and human keratinocytes >

Elastase Inhibitory Activity Assay

Treatment with BJY-PeptaLift-4 showed up to 35.8% inhibition

< Elastase inhibitory activity in normal human dermal fibroblasts (nHDFs) >

Type I Procollagen Production Assay

Treatment with BJY-PeptaLift-4 increased Type I procollagen production by up to 66.9%

< Changes in Type I collagen (COL1A1) gene expression in normal human dermal fibroblasts (nHDFs) >

Crow’s Feet Wrinkle Improvement Study

Treatment with BJY-PeptaLift-4 at 100 ppm resulted in a 21.52% reduction in crow’s feet wrinkles

< Human Application Study Results for Crow’s Feet Wrinkle Improvement with BJY-PeptaLift-4 (100 ppm) >