BJY-PeptaLift-2 is an anti-aging peptide ingredient composed of 18 amino acids. 

It helps improve the appearance of expression wrinkles by modulating signaling pathways involved in muscle contraction.

Improves Expression Wrinkles
Inhibits SNARE complex formation, helping prevent and improve the appearance of expression wrinkles caused by muscle contraction.

Inhibits Muscle Contraction Signaling
At 10 ppm, BJY-PeptaLift-2 inhibited acetylcholine release by 25.13%, thereby reducing signaling associated with muscle contraction.

Skin Penetration
At 50 ppm, penetration to a depth of approximately 150 μm was observed in an artificial skin model after 12 hours.

Improves Eye-Area Wrinkles
In a human application study, use of an eye cream containing 300 ppm BJY-PeptaLift-2 for 4 weeks resulted in a 

21.55% reduction in eye-area wrinkles.

Acetylcholine Secretion Inhibition Assay

Treatment with BJY-PeptaLift-2 at 10 ppm inhibited acetylcholine secretion by 25.13%

< Acetylcholine secretion inhibition assay using a co-culture model of human dermal fibroblasts and human keratinocytes >

Artificial Skin Permeability Analysis Test

Time-dependent peptide skin permeability analysis confirmed penetration to a depth of 

50 μm after 12 hours of treatment

< Skin Permeability Analysis Results of BJY-PeptaLift-2 (50 ppm) >

Crow’s Feet Wrinkle Improvement Study

Treatment with BJY-PeptaLift-2 at 100 ppm resulted in an 11.46% reduction in crow’s feet wrinkles

Treatment with BJY-PeptaLift-2 at 300 ppm resulted in an 21.55% reduction in crow’s feet wrinkles

< Left. Human Application Study Results for Crow’s Feet Wrinkle Improvement with BJY-PeptaLift-2 (100 ppm) >

< Right. Human Application Study Results for Crow’s Feet Wrinkle Improvement with BJY-PeptaLift-2 (300 ppm) >