Peptide Alternative to Botulinum Toxin for Wrinkle Care
BJY-PeptaLift-1 is an anti-aging peptide ingredient composed of 9 amino acids.
It helps improve the appearance of expression wrinkles by modulating signaling pathways involved in muscle contraction.
Improves Expression Wrinkles
Inhibits SNARE complex formation and acetylcholine release, helping improve the appearance of expression wrinkles caused
by muscle contraction.
Improves Skin Elasticity
Inhibited elastase activity by up to 39.7%, helping maintain skin elasticity.
Promotes Collagen Production
Increased a Type I procollagen-related marker by up to 80.55%, helping support collagen production.
Improves Eye-Area Wrinkles
A human application study demonstrated improvement in eye-area wrinkles after 4 weeks of use.
Acetylcholine Secretion Inhibition Assay
Treatment with BJY-PeptaLift-1 at 10 ppm inhibited acetylcholine secretion by 31.46%
< Acetylcholine secretion inhibition assay using a co-culture model of human dermal fibroblasts and human keratinocytes >
SNARE Complex Formation Inhibition Assay
Treatment with BJY-PeptaLift-1 at 150 ppm inhibited SNARE complex formation by 32.32%
< Results of SNARE Complex Formation Induced by SNAP-25, Syntaxin 1A, and VAMP-2 >
Elastase Inhibitory Activity Assay
Treatment with BJY-PeptaLift-1 showed up to 39.7% inhibition
< Elastase Inhibitory Activity in Normal Human Dermal Fibroblasts (nHDFs) >
Type I Procollagen Production Assay
Treatment with BJY-PeptaLift-1 increased Type I procollagen production by up to 80.55%
< Changes in Type I Collagen (COL1A1) Gene Expression in Normal Human Dermal Fibroblasts (nHDFs) >
Crow’s Feet Wrinkle Improvement Study
Treatment with BJY-PeptaLift-1 at 100 ppm resulted in an 8.58% reduction in crow’s feet wrinkles
Treatment with BJY-PeptaLift-1 at 300 ppm resulted in an 11.53% reduction in crow’s feet wrinkles

< Left. Human Application Study Results for Crow’s Feet Wrinkle Improvement with BJY-PeptaLift-1 (100 ppm) >
< Right. Human Application Study Results for Crow’s Feet Wrinkle Improvement with BJY-PeptaLift-1 (300 ppm) >
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