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BJY-PeptaLift-1
Anti-Wrinkle

BJY-PeptaLift-1

Peptide Alternative to Botulinum Toxin for Wrinkle Care

INCI
sr-(Prolyl sh-Polypeptide-145)
Function
Hair Conditioning Agent, Skin Protectant, Skin Conditioning Agent (Moisturizer), Skin Conditioning Agent (Other)
Recommended Dosage
1~300ppm
EWG Score
Grade 1 [Safe]

Product Description

BJY-PeptaLift-1 is an anti-aging peptide ingredient composed of 9 amino acids. 

It helps improve the appearance of expression wrinkles by modulating signaling pathways involved in muscle contraction.

Benefits

Improves Expression Wrinkles
Inhibits SNARE complex formation and acetylcholine release, helping improve the appearance of expression wrinkles caused 

by muscle contraction.


Improves Skin Elasticity
Inhibited elastase activity by up to 39.7%, helping maintain skin elasticity.


Promotes Collagen Production
Increased a Type I procollagen-related marker by up to 80.55%, helping support collagen production.


Improves Eye-Area Wrinkles
A human application study demonstrated improvement in eye-area wrinkles after 4 weeks of use.

Clinical Results

Acetylcholine Secretion Inhibition Assay

Treatment with BJY-PeptaLift-1 at 10 ppm inhibited acetylcholine secretion by 31.46%

 

< Acetylcholine secretion inhibition assay using a co-culture model of human dermal fibroblasts and human keratinocytes >



SNARE Complex Formation Inhibition Assay

Treatment with BJY-PeptaLift-1 at 150 ppm inhibited SNARE complex formation by 32.32%

  

< Results of SNARE Complex Formation Induced by SNAP-25, Syntaxin 1A, and VAMP-2 >



Elastase Inhibitory Activity Assay

Treatment with BJY-PeptaLift-1 showed up to 39.7% inhibition

 

< Elastase Inhibitory Activity in Normal Human Dermal Fibroblasts (nHDFs) >



Type I Procollagen Production Assay

Treatment with BJY-PeptaLift-1 increased Type I procollagen production by up to 80.55%

 

< Changes in Type I Collagen (COL1A1) Gene Expression in Normal Human Dermal Fibroblasts (nHDFs) >



Crow’s Feet Wrinkle Improvement Study

Treatment with BJY-PeptaLift-1 at 100 ppm resulted in an 8.58% reduction in crow’s feet wrinkles

Treatment with BJY-PeptaLift-1 at 300 ppm resulted in an 11.53% reduction in crow’s feet wrinkles

< Left. Human Application Study Results for Crow’s Feet Wrinkle Improvement with BJY-PeptaLift-1 (100 ppm) >

< Right. Human Application Study Results for Crow’s Feet Wrinkle Improvement with BJY-PeptaLift-1 (300 ppm) >

Consent to the Collection and Use of Personal Information

1. BJY collects and uses personal information for the purpose of responding to customer inquiries, as outlined below:

A) Collected Item: Email address
B) Purpose of Use: To respond to customer inquiries
C) Retention Period: Information will be deleted immediately after the purpose is fulfilled
*Your inquiry will not be stored in the system and will be sent directly to the responsible staff via email.

You have the right to refuse consent to the collection and use of your personal information.
However, please note that if you do not consent, we may be unable to provide a response to your inquiry.

2. BJY does not collect or process personal information from individuals under the age of 14.
Therefore, children under 14 are not permitted to submit 1:1 inquiries.